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Healing airways so kids with asthma can breathe better

An exciting study is investigating whether a new therapeutic treatment for asthma will protect young sufferers from ongoing lung damage and improve their long-term health outcomes.

Environmental Exposures

The lungs represent a key interface between the body and the environment.

News & Events

Study unlocks new knowledge about the role of immune cells in asthma flare-ups

Flare-ups of asthma are usually brought on by respiratory infections, such as the common cold, and are one of the most common reasons for a child to miss school or require emergency care.

News & Events

The Kids respiratory researcher wins prestigious prize at 2021 Premier’s Science Awards

The Kids Research Institute Australia researcher, Niamh Troy, has been named a joint winner of the Exxon Mobile Student Scientist of the Year award at the Premier’s Science Awards.

Research

Mucopolysaccharidosis (MPS IIIA) mice have increased lung compliance and airway resistance, decreased diaphragm strength, and no change in alveolar structure

Mucopolysaccharidosis type IIIA (MPS IIIA) is characterized by neurological and skeletal pathologies caused by reduced activity of the lysosomal hydrolase, sulfamidase, and the subsequent primary accumulation of undegraded heparan sulfate (HS). Respiratory pathology is considered secondary in MPS IIIA and the mechanisms are not well understood.