Skip to content
The Kids Research Institute Australia logo
Donate

No results yet

Search

Research

What goes up must come down: dynamics of type 1 interferon signaling across the lifespan

Type 1 interferons (T1IFNs) are typically expressed in low concentrations under homeostatic conditions, but upon pathogenic insult or perturbation of the pathway, these critical immune signaling molecules can become either protectors from or drivers of pathology. While essential for initiating antiviral defense and modulating inflammation, dysregulation of T1IFN signaling can contribute to immunopathology, making it and its associated pathways prime targets for immune evasion and disruption by pathogens. 

News & Events

WA Cystic Fibrosis Research Collaborative Program Grants

New hope is on the horizon for people living with cystic fibrosis.

News & Events

Wal-yan Centre inaugural Shark Tank winners

Congratulations to Dr Montgomery, Dr Iosifidis and Dr D’Vaz on winning the Wal-yan Centre's inaugural seed funding competition.

News & Events

Despite advances in neonatal care, preterm babies have lower lung function throughout their life

Analysis of worldwide research shows that despite advances in neonatal care, preterm babies have lower lung function throughout their life.

News & Events

Community bands together to improve lung health of Aboriginal children in East Kimberley

September marks the three-month milestone of an intensive health promotion campaign in the East Kimberley region, which aims to raise awareness of the dangers of a chronic wet cough in Aboriginal children.